Personalized, EEG-guided TMS when one-size-fits-all is not enough.

How PrTMS is different from standard TMS

Standard FDA-cleared TMS protocols for depression use stimulation parameters that were validated in large clinical trials — a single frequency (typically 10 Hz for high-frequency rTMS), a single anatomic target (typically left dorsolateral prefrontal cortex for depression), and a single course length. Those protocols work, and they are why TMS exists as a treatment option at all.

PrTMS adds a personalization layer on top. Before treatment begins, a clinician records your resting EEG — a non-invasive measurement of your brain's electrical activity at rest. That data informs an individualized stimulation protocol: which frequency makes sense, where to focus, and how often to recalibrate. As the course progresses, EEG measurements may be repeated and the protocol may be adjusted in response to what the brain is showing.

What a PrTMS appointment feels like

The treatment delivery feels similar to standard TMS — you sit awake in a comfortable chair, a coil is placed against your scalp, and brief magnetic pulses are delivered painlessly through the skull. The personalization happens upstream of the delivery, in how the protocol was designed and how it adapts.

Who PrTMS is for

PrTMS may be a fit for patients who:

• Have a clinical picture that does not match the typical profile that drove the standard FDA-cleared protocols (e.g., highly variable mood, mixed features, atypical history).
• Have tried standard-protocol TMS in the past with limited or partial response and want to try an EEG-informed alternative.
• Want a treatment whose intensity and target can adapt as their brain responds, rather than being fixed for the whole course.
• Are exploring neuromodulation for conditions where the standard-protocol evidence is less mature but the clinical rationale is strong.

PrTMS is not a "stronger TMS." It is a different approach to designing the protocol. We are honest about that distinction during evaluation, and we explain the evidence level for your specific condition and history.

Evidence and honest framing

The evidence base for EEG-guided personalized rTMS is more limited than for standard-protocol rTMS, particularly for indications outside major depression. We say this clearly because we are not interested in over-selling a treatment. The clinical case for PrTMS, when it is the right fit, is that it tailors a real and well-studied mechanism (rTMS) to the individual patient's neural data — not that it represents a different or better mechanism than standard TMS.

Where the evidence base for a specific use of PrTMS is genuinely limited (for example, in autism spectrum support), we say so during the evaluation and discuss the rationale, the risk profile, and the alternatives before recommending it.

What a PrTMS course looks like at MyNeuPath

1. Clinical evaluation. A psychiatrist or PMHNP reviews your prior treatment, current symptoms, medical history, and whether PrTMS or standard TMS makes more sense for you.
2. Baseline EEG. If PrTMS is the chosen approach, a resting EEG is recorded to inform the personalized stimulation protocol.
3. Insurance verification. Coverage for personalized rTMS varies by payer. We verify benefits and explain out-of-pocket cost before scheduling treatment.
4. Treatment course. Regular sessions over several weeks. Like standard TMS, you are awake, seated, and can return to ordinary activity afterward.
5. Periodic EEG review. The personalization layer may include repeating EEG and adjusting the protocol as the brain responds.
6. Clinical check-ins. Your prescribing clinician reviews progress at set intervals and discusses next steps as the course winds down.

[CONFIRM: which PrTMS / PeakLogic device or workflow MyNeuPath specifically delivers, the typical course length quoted to patients, and which patient profiles Dr. Roumani considers strongest candidates.]